Orthodontic treatment time: can it be shortened?

Multiple-breath washout measurements can be significantly shortened in children.

Multiple-breath washout (MBW)-derived lung clearance index (LCI) is a sensitive measure of ventilation inhomogeneity in patients with cystic fibrosis (CF), but LCI measurement is time consuming. We systematically assessed ways to shorten LCI measurements. In 68 school-aged children (44 with mild CF lung disease) three standard nitrogen (N2) MBWs were applied. We assessed repeatability and diagn...

Can the duration of tuberculosis treatment be shortened with higher dosages of rifampicin?

Strategies involving new applications of existing drugs are urgently needed to reduce the time required to cure patients with drug-susceptible and drug-resistant tuberculosis (TB). Use of high-dosage rifampicin is one such approach. Recent data from preclinical animal models (Hu et al., 2015) and clinical studies (Boeree et al., 2015) support a potential role for highdosage rifampicin in TB che...

It can be smart to be dumb

An important problem in game theory is why bounded rationality occurs, e.g., why altruism to non-kin occurs. Previous explanations involved computational limitations of the players, repeated play among the players etc. As an alternative, we introduce a pre-play step in which each player i chooses a “persona”, i.e., a ficticious utility function she commits to use in the game. By adopting differ...

Chromium: can it be useful in treatment of DHF ?

Learning can ’ t be fun , can it ?

Inspired by research by Carrie Heeter et al. and the MIT Games-to-Teach project we set up a small scale empirical study on two educational games on Art aimed at primary school children. We found that both boys and girls liked to play these games; that one game scored better on our ‘fun-index’ and that girls had less mouse skills and lacked certain game skills. This did not, however, affect thei...